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INFLAMMATORY BOWEL DISEASE

Ulcerative colitis and Crohn's Disease Contd....

About the author

Dr. Minocha (http://www.diagnosishealth.com/minocha.htm) is the Professor of Medicine and Director, Division of Digestive Diseases at the University of Mississippi Medical Center in Jackson, MS, and is the author of How to Stop Heartburn; Simple Ways to Heal Heartburn and Acid Reflux.


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  • Infliximab (Remicade) is an exciting new addition. It is a monoclonal antibody against tumor necrosis factor alfa. It is given as a single iv infusion of 5mg/kg over 2 hours for moderate to severe active Crohn's disease unresponsive to conventional treatment. In cases of fistulizing Crohn's disease, the initial dose is repeated at 2 and 6 weeks. Side effects: infections, lupus like syndrome, Infusion related reaction, digestive upset.

   

 
 

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RELATED PUBLICATIONS BY DR. MINOCHA.....


1. Minocha et al. Acute Sulfasalazine Overdose. Journal of Toxicology Clinical Toxicolgy 1991.

2. Minocha et al. Small Bowel Endometriosis Masquerading as Regional Enteritis. Digestive Diseases and Sciences 1994.

3. Minocha et al. Lack Of Crucial Role of Mast Cells in Pathogenesis of Experimental Colitis in Mice. Digestive Diseases and Sciences 1995.

4. Minocha A et al.: Crohn's Disease Complicating Male Genitourinary Tract Without Overlying Cutaneous Involvement. Am J Gastroenterol 1996.

5. Minocha A et al.: Role of Appendectomy and Tonsillectomy in Pathogenesis of Ulcerative Colitis. Digestive Diseases And Sciences 1997.

 


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